Senior Staff Software Engineer, Dyno Therapeutics
Full Stack
Office located in Watertown, MA
AI-powered gene therapy
Open for applications
AI-powered gene therapy
101-200 employees
Open for applications
Office located in Watertown, MA
101-200 employees
Company mission
To use machine learning and quantitative experimentation to invent new ways to design gene vectors.
Role
Who you are
- Trusted partner
- Team oriented
- Thoughtful & detail oriented
- Work with a sense of urgency
- Excited about building amazing product experiences that wow scientists
- Appreciation for opportunities at the intersections of data science and biology
- Comfortable with rapid iteration and shifting priorities
- Strong programming and system design fundamentals with 4+ years of experience with full stack development
- Developing frontend applications using modern frameworks such as React (or other comparable frameworks such as Vue.js, Svelte, etc.)
- Backend system design & development from DB to API
- Experience working cross-team to communicate with both technical and business stakeholders as well as customers
Desirable
- Experience with Python backend development (examples include: Django, FastAPI, Flask, etc.)
- Demonstrated examples of applying product taste
- Excitement about (but not necessarily experience with) building products that let scientists do more, faster
- Experience building on top of ML models and/or LLMs
- Have built products in the 0-1 stage
- Even limited experience managing cloud deployments and environments
- Excited to learn about bio/gene therapy (no experience necessary)
What the job involves
- Dyno is seeking an experienced full stack engineer to lead development of new internal and external products for designing genetic sequences that strengthen Dyno’s position
- As a Senior/Staff Software Engineer - Full Stack on the ML Products Team, you will be a core contributor to new products that will amplify scientists’ capabilities and impact on patients
- You’ll build across the stack, ranging from database interfaces, scalable backend web services, frontend development, and incorporating ML models and LLMs into products
- Lead end-to-end development of new products for genetic sequence design within the ML Products team
- Iterating on ideas and prototypes and then prioritizing the path to an MVP
- Develop and disseminate best practices for repeatable and scalable end to end product development
- Collaborate with team members ranging from engineers, computational biologists, ML researchers, and biologists to come up with and build great products
- Mentor and teach other engineers on the team
Our take
Gene therapy has the potential to revolutionize healthcare, but the effectiveness of these treatments is currently limited by the naturally occurring vectors (methods of transport for DNA) that scientists have available. Dyno Therapeutics is pioneering an AI-powered approach to gene therapy, that combines machine learning with quantitative high-throughput in vivo experimentation to produce targeted vectors that enable the treatment of a wide range of diseases.
Dyno's CapsidMap platform is capable of creating new and optimized AAV vectors, which are the most common method of delivery for gene therapy for human diseases. It is currently building up a portfolio of these vectors and, in 2021, partnered with Astellas to develop ones specified to skeletal and cardiac muscle. The company has raised impressive funds that will enable it to build out its team and seek new partnerships, as well as expand its platform into as-yet-unserved tissues.
Steph
Company Specialist at Welcome to the Jungle
Insights
Company
Funding (2 rounds)
May 2021
$100m
SERIES A
May 2020
$9m
SEED
Total funding: $109m
Company benefits
- Health & dental insurance through BCBS
- Vision coverage Health Savings Account
- Life Insurance & Disability Coverage
- 401(k) plan
- Access to KGA Life Services, which includes counseling, financial & legal consultations, and referrals for a wide range of services
- 20 vacation days
- Unlimited sick days
- 40 hours of time off for volunteer work
- 12 paid holidays
- Parental leave
- New facility in Watertown, MA
- Free on-site lunch daily
- Commuter benefits
- Free on-site parking
Company values
- Respect: We recognize the unique contributions of each individual and assume the best intent.
- Openness: We share decisions, successes, and failures transparently and honestly to enable others to do their best work.
- Support: We are mindful of others’ needs and well-being.
- Boldness: We fearlessly tackle ambitious scientific and organizational challenges in creative ways.
- Rigor: We practice a thorough and intentional approach to work to generate clearly interpretable results.
- Dedication to teamwork: We succeed as diverse, committed, and accountable teams.
- Empowering individuals: We enable professional growth through support of autonomy, cross-functional understanding and thoughtful risk-taking.
- Collaboration: We actively promote interaction between teams to stimulate innovation and learning.
- Sustainable success: We strive for long-term excellence by balancing joyful and fulfilling work with time to unplug.
Company HQ
Watertown, MA
Articles
Leadership
Eric Kelsic
(CEO)Former Staff Scientist at the Wyss Institute for Biologically Inspired Engineering. PhD in Systems Biology from Harvard.
Sam Sinai
(ML Research Lead)Previously a Graduate Research Assistant at the Wyss Institute for Biologically Inspired Engineering. PhD in Mathematical and Computational Biology from Harvard.
Tomas Björklund
(Scientific Advisor)Professor of Neuroscience at Lund University. Former COO of Genepod Therapeutics.
Adrian Veres
(Scientific Co-Founder)Postdoctoral Research Fellow at Harvard, with a PhD in Systems Biology.
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