Lead Software Engineer, PostEra
Platform
$190-220k
Equity: 0.10% - 0.20%
More information about location
Medical chemistry powered by machine learning
Open for applications
Medical chemistry powered by machine learning
21-100 employees
Open for applications
$190-220k
Equity: 0.10% - 0.20%
More information about location
21-100 employees
Company mission
To accelerate the discover of new cures for patients.
Role
Who you are
- 5+ years of experience and a bachelor's degree (or more advanced education) to succeed in this role
- Experience in systems design and backend web development
- An interest in technical mentorship and management
Desirable
- Expertise in a python based backend web framework (we use Django, for example)
- Experience integrating ML systems into production services/software
- Familiarity with container orchestration or workflow systems (like: Kubernetes, Kubeflow, Argo, Airflow)
- Have some familiarity with data pipelines
- Experience with designing agentic workflows/context engineering
- Past roles with technical mentorship focus or people management responsibilities
What the job involves
- In this role, you will be helping PostEra deliver on its mission of getting therapies to patients by shaping systems design decisions around our drug discovery platform, Proton
- Design focus areas include things like data architecture, microservice design, and patterns for running async compute-heavy ML jobs
- In addition, you will keep close to the codebase by helping build and improve the platform upon which our team delivers features
- You will lead by example, championing best practices in software development and engineering culture, while also spearheading innovative projects that push the boundaries of drug discovery
- You will make well thought out decisions about system architecture, including API design, application boundaries, and microservice communication
- These systems should support the Proton platform in its pursuit to trivially handle many concurrent drug discovery projects running in parallel at industry-leading speed
- Your leadership style should foster an environment of learning and improvement within our engineering team in which you should strive to build technical rapport with colleagues through coding and code review
- Technical Leadership and Execution: Lead the architectural design and contribute to the development of scalable web applications and microservices. Deep technical knowledge and professional experience:
- Using cloud providers (ideally AWS), container orchestration frameworks, and IaC best practices
- Working with teams who ship products using web-dev stacks composed of Python, modern frontend frameworks, and relational databases like PostgreSQL. Mentorship and Collaboration: Play a pivotal role in mentoring engineers, promoting a culture of cross-team collaboration and continuous learning.
- Be instrumental in facilitating knowledge sharing sessions, code reviews, and defining team-wide technical standards
- Projects You May Lead:
- Innovative Drug Discovery Projects: Collaborate with scientists and ML experts to tackle challenges directly contributing to the discovery of novel medicines. Specific challenges may include projects such as expanding molecular search to 100B+ scale, designing automated AI-medicinal-chemist workflows, bringing novel ML research to production, and creating tools for real-time data analysis in drug design processes
- Engineering Excellence Initiatives: Drive projects focused on enhancing our engineering framework such as architecting backend interactions with ML systems, improving our CI/CD processes, setting new standards for code quality and testing, incorporating AI tooling into our development processes, and implementing monitoring solutions that offer real-time insights into our applications' performance
- Hiring Manager: Matt Robinson
Our take
PostEra is a biotechnology company using AI to help speed up the process of discovering new medicines. Its core platform, Proton, is designed to support medicinal chemistry by helping researchers design and optimize drug candidates more efficiently, with the goal of reducing the time and cost it takes to bring new treatments to patients.
The company works closely with major pharmaceutical partners to apply its technology to real-world drug development programs. It has also continued to build momentum through deeper collaboration with Pfizer, expanding both its existing AI Lab partnership and launching a new antibody-drug-conjugate (ADC) programme. The work centres on tis Proton platform, which is being used to accelerate and improve early-stage drug discover across both small molecules and more complex therapies.
This growing adoption highlights increasing confidence in PostEra's AI-driven approach to medicinal chemistry. With over $1B in partnership value across multiple biopharma collaborations and continues expansion of its pipelines, the company is ready to cement its place as a long-term player in AI-enabled drug development.
Steph
Company Specialist at Welcome to the Jungle
Company
Funding (2 rounds)
Jan 2022
$24m
SERIES A
Mar 2020
$0.2m
SEED
Total funding: $24.2m
Company HQ
North End, Boston, MA
Leadership
Aaron Morris
(Co-Founder & CEO)Prior to co-founding PostEra in 2019, Aaron spent over 5 years at Goldman Sachs as a Risk Analyst, Equity Derivatives Trader and ultimately as an Equity Trader.
Alpha Lee
(Co-Founder & CSO)Alpha is a Faculty Member at the University of Cambridge, a role they've held since 2017. Previously, they were a Scientific co-founder of Byterat.
Matt Robinson
(Co-Founder & CTO)Previously did research in Biomolecular Simulation and Machine Learning for Drug Discovery at Yale University and University of Cambridge, before co-founding PostEra.
Share this job